• Adding marrow adiposity and cortical porosity to femoral neck areal bone mineral density improves the discrimination of women with nonvertebral fractures from controls 

      Zebaze, Roger; Osima, Marit; Bui, Minh; Lukic, Marko; Wang, Xiaofang; Ghasem-Zadeh, Ali; Eriksen, Erik Fink; Vais, Angela; Shore-Lorenti, Catherine; Ebeling, Peter R.; Seeman, Ego; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-18)
      Advancing age is accompanied by a reduction in bone formation and remodeling imbalance, which produces microstructural deterioration. This may be partly caused by a diversion of mesenchymal cells towards adipocytes rather than osteoblast lineage cells. We hypothesized that microstructural deterioration would be associated with an increased marrow adiposity, and each of these traits would be independently ...
    • Adiposity Without Obesity: Associations with Osteoporosis, Sarcopenia, and Falls in the Healthy Ageing Initiative Cohort Study 

      Scott, David; Johansson, Jonas; Ebeling, Peter R.; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-23)
      Objective - Obesity is commonly defined by BMI rather than adiposity, which may have differential effects on musculoskeletal health. Musculoskeletal outcomes were compared in older adults with normal adiposity and normal BMI (NA‐NBMI), those with high adiposity but normal BMI (HA‐NBMI), and those with high adiposity and high BMI (HA‐HBMI).<p> <p>Methods - In 3,411 70‐year‐olds, obesity was defined ...